翻訳と辞書 Words near each other ・ Phetharbital ・ Phetkasem Road ・ Phetmorakot wor sangprapai ・ Phetogo Molawa ・ Phetracha ・ Phetsarath Ratanavongsa ・ Phetus ・ Pheu Thai Party ・ Pheucticus ・ Pheugopedius ・ Pheung Kya-shin ・ PhEVER ・ Phew ・ Phew (singer) ・ Phewa Lake ・ PHEX ・ Phex ・ Phey ・ Phezulu Emafini ・ PHF ・ PHF1 ・ PHF10 ・ PHF12 ・ PHF16 ・ PHF17 ・ PHF20 ・ PHF21A ・ PHF3 ・ PHF6 ・ PHF8 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク PHEX ： ウィキペディア英語版 PHEX Phosphate-regulating neutral endopeptidase, X-linked also known as phosphate-regulating gene with homologies to endopeptidases on the X chromosome or metalloendopeptidase homolog PEX is an enzyme that in humans is encoded by the PHEX gene. This gene contains 18 exons and is located on the X chromosome. == Function == The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5251 )〕 The bone and dentin protein osteopontin (OPN) which inhibits mineralization in the skeleton and in teeth is a substrate for PHEX. In the absence of functional PHEX in the mouse model (Hyp) of X-linked hypophosphatemia, in addition to renal phosphate wasting, osteopontin and osteopontin fragments accumulate in bone and may contribute to the osteomalacia characteristic of XLH/HYP. XLH patients have soft and deformed skeletons and soft teeth that easily become infected. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「PHEX」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.