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PLXNA2
Plexin-A2 is a protein that in humans is coded by the ''PLXNA2'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5362 )〕 This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C.〔 In some studies, the PLXNA2 gene is associated with schizophrenia.〔(Gene Overview of All Published Schizophrenia-Association Studies for PLXNA2 ) - база данных SZGene, сайт Schizophrenia Research Forum〕 and anxiety. ==References==
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