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・ Priče o životu
・ Pričevac
・ Pričević
・ Priştine Detachment
・ Prižba
・ Prișca River
・ PRK
・ PRK Hekari United
・ PRKAA2
・ PRKAB1
・ PRKAB2
・ PRKACA
・ PRKACB
・ PRKACG
・ PRKAG1
PRKAG2
・ PRKAG3
・ PRKAR1A
・ PRKAR1B
・ PRKAR2A
・ PRKAR2B
・ PRKCB1
・ PRKCD
・ PRKCE
・ PRKCG
・ PRKCH
・ PRKCI
・ PRKCQ
・ PRKCSH
・ PRKD2


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PRKAG2 : ウィキペディア英語版
PRKAG2

5'-AMP-activated protein kinase subunit gamma-2 is an enzyme that in humans is encoded by the ''PRKAG2'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51422 )
== Function ==

AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four CBS domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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