翻訳と辞書 Words near each other ・ Pričević ・ Priştine Detachment ・ Prižba ・ Prișca River ・ PRK ・ PRK Hekari United ・ PRKAA2 ・ PRKAB1 ・ PRKAB2 ・ PRKACA ・ PRKACB ・ PRKACG ・ PRKAG1 ・ PRKAG2 ・ PRKAG3 ・ PRKAR1A ・ PRKAR1B ・ PRKAR2A ・ PRKAR2B ・ PRKCB1 ・ PRKCD ・ PRKCE ・ PRKCG ・ PRKCH ・ PRKCI ・ PRKCQ ・ PRKCSH ・ PRKD2 ・ PRKD3 ・ PRKG1 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク PRKAR1A ： ウィキペディア英語版 PRKAR1A cAMP-dependent protein kinase type I-alpha regulatory subunit is an enzyme that in humans is encoded by the ''PRKAR1A'' gene. == Function == cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase A (PKA), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of PKA is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of PKA have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids Three alternatively spliced transcript variants encoding the same protein have been observed.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5573 )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「PRKAR1A」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.