翻訳と辞書 Words near each other ・ Pseudagrion sublacteum ・ Pseudagrion sudanicum ・ Pseudagrion superbum ・ Pseudagrion torridum ・ Pseudagrion vumbaense ・ Pseudagrostistachys ・ Pseudagrostistachys africana ・ Pseudalastor ・ Pseudalbara ・ Pseudalbara fuscifascia ・ Pseudalbara parvula ・ Pseudalcathoe ・ Pseudalcis ・ PSEmu Pro ・ PSEN1 ・ PSEN2 ・ Psenes ・ Psenicubiceps ・ Psenocerus supernotatus ・ Psenopsis ・ Psephis ・ Psephis gomalis ・ Psephis ministralis ・ Psephis myrmidonalis ・ Psephite ・ Psephochelys ・ Psephoderma ・ Psepholograph ・ Psephology ・ Psephophorus Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク PSEN2 ： ウィキペディア英語版 PSEN2 Presenilin-2 is a protein that in humans is encoded by the ''PSEN2'' gene. == Function == Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Two alternative transcripts of PSEN2 have been identified.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5664 )〕 In melanocytic cells PSEN2 gene expression may be regulated by MITF. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「PSEN2」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.