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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク PSMD7 ： ウィキペディア英語版 PSMD7 26S proteasome non-ATPase regulatory subunit 7 , also known as 26S proteasome non-ATPase subunit Rpn8,is an enzyme that in humans is encoded by the ''PSMD7'' gene.〔 The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. == Gene == The gene ''PSMD7'' encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5713 )〕 The human gene ''PSMD7'' has 7 Exons and locates at chromosome band 16q22.3. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「PSMD7」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.