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・ PTP (band)
・ PTP4A1
・ PTP4A2
・ PTP4A3
・ PTPd
・ PTPL College
・ PTPLAD1
・ PTPN1
・ PTPN11
・ PTPN12
・ PTPN13
・ PTPN14
・ PTPN18
・ PTPN2
・ PTPN21
PTPN22
・ PTPN23
・ PTPN3
・ PTPN4
・ PTPN5
・ PTPN6
・ PTPN7
・ PTPN9
・ PTPRA
・ PTPRB
・ PTPRC
・ PTPRCAP
・ PTPRD
・ PTPRE
・ PTPRF


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PTPN22 : ウィキペディア英語版
PTPN22

Protein tyrosine phosphatase, non-receptor type 22 (lymphoid), also known as PTPN22, is a protein that in humans is encoded by the ''PTPN22'' gene. This gene can be expressed in different forms. PTPN22 affects the responsiveness of T and B cell receptors, and mutations are associated with increases or decreases in risks of autoimmune diseases.
==Molecular biology==
The gene is located on the short arm of Chromosome 1 near the end (telomere) (1p13.2) on the Crick (minus) strand. It is 57,898 bases in length and encodes a protein of 807 amino acids (molecular weight 91,705 Da). There are 24 exons in the gene and 21 transcript variants encoding 10 distinct proteins are known. The proteins are located in the cytoplasm.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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