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PTTG1IP
Pituitary tumor-transforming gene 1 protein-interacting protein (PTTG1), also known as PTTG1-binding factor (PBF), is a poorly characterised protein that in humans is encoded by the ''PTTG1IP'' gene 〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=754 )〕 located within the chromosomal region 21q22.3. == Structure ==
The encoded protein is composed of 180 amino acids and has a predicted molecular mass of 22kDa. The peptide sequence shares no significant homology with any other human proteins but is highly conserved across a wide diversity of animal species, suggesting both unique function and evolutionary importance.〔 Initial protein prediction studies suggested that PTTG1IP was a cell surface glycoprotein, however, the recent identification of a nuclear localisation signal (NLS) suggests that it may have a role both in the cytoplasm and as a nuclear protein.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「PTTG1IP」の詳細全文を読む
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