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PVT1
Pvt1 oncogene (non-protein coding), also known as PVT1, is a long non-coding RNA gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5820 )〕 In mice, this gene was identified as a breakpoint site in chromosome 6;15 translocations. These translocations are associated with murine plasmacytomas.〔 〕 The equivalent translocation in humans is t(2;8), which is associated with a rare variant of Burkitt's lymphoma.〔 〕 In rats, this breakpoint was shown to be a common site of proviral integration in retrovirally induced T lymphomas.〔 〕 Transcription of PVT1 is regulated by Myc.〔 〕
==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「PVT1」の詳細全文を読む
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