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Paeonol Paeonol is a phenolic compound found in peony such as ''Paeonia suffruticosa'' (moutan cortex), in ''Arisaema erubescens'', and in ''Dioscorea japonica''. It is a component found in many Traditional Chinese medicine remedies. == Biological effects == Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's disease. Paeonol also reduced cerebral infarction involving the superoxide anion and microglia activation in ischemia-reperfusion injured rats. It shows antimutagenic activities.〔〔 It also has anti-inflammatory and analgesic effects in carrageenan-evoked thermal hyperalgesia. Paeonol inhibits anaphylactic reaction by regulating histamine and TNF-α. It has demonstrated significant MAOI activity. MAO-A and MAO-B inhibiting effects with IC50 values of 54.6 μM and 42.5 μM respectively.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Paeonol」の詳細全文を読む
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