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Parabutoxin
Parabutoxin (PBTx) is a Shaker-related voltage-gated K+ channel (Kvα1) inhibitor purified from different ''Parabuthus'' scorpion species found in southern Africa. It occurs in different forms: parabutoxin 1 (PBTx1), parabutoxin 2 (PBTx2), parabutoxin 3 (PBTx3) and parabutoxin (PBTx10). The different variants have different affinities towards Kvα1 channels. ==Sources== Four different acidic peptides (PBTx1, PBTx2, PBTx3 and PBTx10) have been isolated and cloned from the venoms of three different ''Parabuthus'' scorpion species found in southern Africa. PBTx1 and PBTx3 were extracted from the venom of ''P. transvaalicus'', PBTx2 from ''P. villosus'' and PBTx10 has been purified from ''P. granulatus''.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Parabutoxin」の詳細全文を読む
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