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Penciclovir
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Penciclovir : ウィキペディア英語版
Penciclovir

Penciclovir (INN) is a guanosine analogue antiviral drug used for the treatment of various herpesvirus infections. It is a nucleoside analogue which exhibits low toxicity and good selectivity. Because penciclovir is absorbed poorly when given orally (by mouth) it is used more as a topical treatment, and is the active ingredient in the cold sore medications Denavir (NDC 0135-0315-52), Vectavir and Fenivir. Famciclovir is a prodrug of penciclovir with improved oral bioavailability.
==Efficacy==
In herpes labialis, the duration of healing, pain and detectable virus is reduced by up to one day,〔[http://www.fass.se/LIF/produktfakta/artikel_produkt.jsp?NplID=19970117000027&DocTypeID=7&UserTypeID=2 Farmaceutiska Specialiteter i Sverige - the Swedish official drug catalog. [http://www.fass.se Fass.se] --> Vectavir. Retrieved on August 12, 2009. Translated from "Tiden för läkning, smärta och påvisbart virus förkortas med upp till ett dygn."〕 compared with the total duration of 2–3 weeks of disease presentation.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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