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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Phenylahistin ： ウィキペディア英語版 Phenylahistin Phenylahistin is a metabolite produced by the fungus ''Aspergillus ustus'' that belongs to a class of naturally occurring 2,5-diketopiperazines featuring a dehydrohistidine residue that exhibit important biological activities, such as anti-cancer or neurotoxic effects. Phenylahistin is a microtubule binding agent that exhibits cytotoxic activities against a wide variety of tumor cell lines. A series of synthetic analogs were prepared to remove the chirality and optimize biological activity. These studies led to the potent anti-tumor agent plinabulin, which is active in multidrug-resistant (MDR) tumor cell lines. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Phenylahistin」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.