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・ Phosphoryl chloride
・ Phosphoryl chloride (data page)
・ Phosphoryl fluoride
・ Phosphoryl group
・ Phosphoglycolate phosphatase
・ Phosphogypsum
・ Phosphohydroxypyruvic acid
・ Phosphoinositide 3-kinase
・ Phosphoinositide 3-kinase inhibitor
・ Phosphoinositide 5-phosphatase
・ Phosphoinositide phospholipase C
・ Phosphoinositide-dependent kinase-1
・ Phosphoketolase
・ Phospholamban
・ Phosphole
Phospholipase
・ Phospholipase A
・ Phospholipase A1
・ Phospholipase A2
・ Phospholipase B
・ Phospholipase C
・ Phospholipase D
・ Phospholipase D1
・ Phospholipid
・ Phospholipid acyltransferase
・ Phospholipid scramblase
・ Phospholipid transfer protein
・ Phospholipid-derived fatty acids
・ Phospholipid-hydroperoxide glutathione peroxidase
・ Phospholipid-translocating ATPase


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Phospholipase : ウィキペディア英語版
Phospholipase

A phospholipase is an enzyme that hydrolyzes phospholipids into fatty acids and other lipophilic substances. There are four major classes, termed A, B, C and D, distinguished by the type of reaction which they catalyze:
*Phospholipase A
*
*Phospholipase A1 - cleaves the SN-1 acyl chain.
*
*Phospholipase A2 - cleaves the SN-2 acyl chain, releasing arachidonic acid.
*Phospholipase B - cleaves both SN-1 and SN-2 acyl chains; this enzyme is also known as a lysophospholipase.
*Phospholipase C - cleaves before the phosphate, releasing diacylglycerol and a phosphate-containing head group. Phospholipase Cs play a central role in signal transduction, releasing the second messenger inositol triphosphate.
*Phospholipase D - cleaves after the phosphate, releasing phosphatidic acid and an alcohol.
Types C and D are considered phosphodiesterases.
Phospholipase A2 acts on the intact lecithin molecule and hydrolyses the fatty acid esterified to the second carbon atom. The resulting products are lysolecithin and a fatty acid. Phospholipase A2 is an enzyme present in the venom of bees and viper snakes.〔D. M. Vasudevan & S. Sreekumari, ''Textbook of Biochemistry'' (5th ed.)〕
==See also==

*Patatin-like phospholipase
*Infantile neuroaxonal dystrophy

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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