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Physiology (; 〔(【引用サイトリンク】url=http://www.etymonline.com/index.php?term=physiology&allowed_in_frame=0 )〕) is the scientific study of the normal function in living systems. A sub-discipline of biology, its focus is in how organisms, organ systems, organs, cells, and bio-molecules carry out the chemical or physical functions that exist in a living system. Given the size of the field it is divided into, among others, animal physiology (including that of humans), plant physiology, cellular physiology, microbial physiology (see microbial metabolism), bacterial physiology, and viral physiology.〔 Nobel Prize in Physiology or Medicine is awarded to those who make significant achievements in this discipline since 1901 by the Royal Swedish Academy of Sciences. In medicine, a physiologic state is one occurring from normal body function, rather than pathologically, which is centered on the abnormalities that occur in animal diseases, including humans.〔(【引用サイトリンク】title=What is physiology? )〕 ==History== Physiological studies date back to ancient civilizations of India, Egypt alongside anatomical studies but did not utilize dissections and vivisection.〔(【引用サイトリンク】title=Medicine Across Cultures )〕 The study of human physiology as a medical field dates back to at least 420 BC to the time of Hippocrates, also known as the "father of medicine." Hippocrates incorporated his belief system called the theory of humours, which consisted of four basic substance: earth, water, air and fire. Each substance is known for having a corresponding humour: black bile, phlegm, blood and yellow bile, respectively. Hippocrates also noted some emotional connections to the four humours, which Claudis Galenus would later expand on. The critical thinking of Aristotle and his emphasis on the relationship between structure and function marked the beginning of physiology in Ancient Greece. Like Hippocrates, Aristotle took to the humoral theory of disease, which also consisted of four primary qualities in life: hot, cold, wet and dry.〔(【引用サイトリンク】title=Early Medicine and Physiology )〕 Claudius Galenus (c. ~130–200 AD), known as Galen of Pergamum, was the first to use experiments to probe the functions of the body. Unlike Hippocrates though, Galen argued that humoral imbalances can be located in specific organs, including the entire body.〔(【引用サイトリンク】title=Galen of Pergamum )〕 His modification of this theory better equipped doctors to make more precise diagnoses. Galen also played off of Hippocrates idea that emotions were also tied to the humours, and added the notion of temperaments: sanguine corresponds with blood; phlegmatic is tied to phlegm; yellow bile is connected to choleric; and black bile corresponds with melancholy. Galen also saw the human body consisting of three connected systems: the brain and nerves, which are responsible for thoughts and sensations; the heart and arteries, which give life; and the liver and veins, which can be attributed to nutrition and growth.〔 To top it off, Galen was also the founder of experimental physiology. And for the next 1,400 years, Galenic physiology was a powerful and influential tool in medicine.〔 Jean Fernel (1497–1558), a French physician, introduced the term "physiology". In the 19th century, physiological knowledge began to accumulate at a rapid rate, in particular with the 1838 appearance of the Cell theory of Matthias Schleiden and Theodor Schwann. It radically stated that organisms are made up of units called cells. Claude Bernard's (1813–1878) further discoveries ultimately led to his concept of ''milieu interieur'' (internal environment), which would later be taken up and championed as "homeostasis" by American physiologist Walter B. Cannon in 1929. By homeostasis, Cannon meant "the maintenance of steady states in the body and the physiological processes through which they are regulated."〔Theodore M. Brown and Elizabeth Fee, “Walter Bradford Cannon: Pioneer Physiologist of Human Emotions” in ''American Journal of Public Health''. 2002 October; 92(10): 1594–1595. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1447286/〕 In other words, the body's ability to regulate its internal environment. It should be noted that, William Beaumont was the first American to utilize the practical application of physiology. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Physiology」の詳細全文を読む スポンサード リンク
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