翻訳と辞書 Words near each other ・ Phytophthora infestans ・ Phytophthora inflata ・ Phytophthora iranica ・ Phytophthora katsurae ・ Phytophthora kernoviae ・ Phytophthora lateralis ・ Phytophthora medicaginis ・ Phytophthora megakarya ・ Phytophthora megasperma ・ Physostegania ・ Physostegia ・ Physostegia correllii ・ Physostegia virginiana ・ Physostigma ・ Physostigma venenosum ・ Physostigmine ・ Physostome ・ Phystis ・ Physula ・ Physula albipunctilla ・ Physulodes ・ Physwick Hostel, Cambridge ・ PhysX ・ Physynth ・ Phytala ・ Phytalmia ・ Phytalmia mouldsi ・ Phytalmiinae ・ Phytalus ・ Phytanate—CoA ligase Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Physostigmine ： ウィキペディア英語版 Physostigmine Physostigmine (also known as eserine from ''éséré'', the West African name for the Calabar bean) is a parasympathomimetic alkaloid, specifically, a reversible cholinesterase inhibitor. It occurs naturally in the Calabar bean. The chemical was synthesized for the first time in 1935 by Percy Lavon Julian and Josef Pikl. It is available in the U.S. under the trade names Antilirium and Isopto Eserine, and as eserine salicylate and eserine sulfate. Today, physostigmine is most commonly used for its medicinal value but before its discovery by western medicine in 1846 it was much more prevalent as a poison. Physostigmine has an LD50 of 3 mg/kg in mice. == Pharmacology == Physostigmine acts by interfering with the metabolism of acetylcholine. It is a covalent (reversible - bond hydrolyzed and released) inhibitor of acetylcholinesterase, the enzyme responsible for the breakdown of acetylcholine in the synaptic cleft of the neuromuscular junction. It indirectly stimulates both nicotinic and muscarinic acetylcholine receptors. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Physostigmine」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.