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Piribedil
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Piribedil : ウィキペディア英語版
Piribedil

Piribedil (trade names Pronoran, Trivastal Retard, Trastal, Trivastan, Clarium and others) is an antiparkinsonian agent and piperazine derivative which acts as a D2 and D3 receptor agonist. It also has α2-adrenergic antagonist properties.
== Indications ==

* Treatment of Parkinson's disease (PD), either as monotherapy (without levodopa)) or in combination with L-DOPA therapy, in the early stages of the disease as well as in the advanced ones
* Treatment of pathological cognitive deficits in the elderly (impaired attention, motivation, memory, etc.)
* Treatment of dizziness in the elderly
* Treatment of retinal ischemic manifestations
* Adjunctive treatment of intermittent claudication due to peripheral vascular disease (PVD) of the lower limbs (stage 2)
* Adjunctive treatment of anhedonia and treatment-resistant depression in unipolar and bipolar depressives (''off label'')
* Treatment of gait disorders associated with Parkinson's disease (no related cause) and other forms of parkinsonism

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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