翻訳と辞書 Words near each other ・ Piruna roeveri ・ Pirunkieli ・ Pirus ・ Piruz ・ Piruz Dilanchi ・ Piruz Khosrow ・ Pirojsha Godrej ・ Pirojsha Godrej (businessman) ・ Pirok ・ Pirolate ・ Pirolazamide ・ Pirolito ・ Pirom Un-prasert ・ Piromalli 'ndrina ・ Piroman ・ Piromelatine ・ Piromidic acid ・ Piromyces ・ Piron ・ Pironchamps ・ Pirongia ・ Pirongia Forest Park ・ Pirooz ・ Piroozi ・ Piroozi Metro Station ・ Piroplasmida ・ Piroplasmosis ・ Piroska Budai ・ Piroska Szamoránsky ・ Piroska Szekrényessy Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Piromelatine ： ウィキペディア英語版 Piromelatine Piromelatine (Neu-P11) is a multimodal sleep drug under development by Neurim Pharmaceuticals. It is an agonist at melatonin MT1/MT2 and serotonin 5-HT1A/5-HT1D receptors. Nuerim is doing a phase II randomized, placebo controlled trial of cognitive and sleep effects in Alzheimer's disease. Results of a phase II trial on insomnia in 120 adults were announced in 2013, finding piromelatine 20/50 mg improved sleep over 4 weeks vs placebo.〔http://www.neurim.com/news/2013-02-18/positive-phase-2-clinical-trial-results-of-piromelatine-for-the-treatment-of-insomnia/〕 Phase 1A/1B studies in 2011, showed safe dose-dependent improvement in sleep.〔http://www.neurim.com/news/2011-07-24/positive-results-from-phase-i-and-ib-clinical-trials-with-neu-p11/〕 Pre-clinical studies showed antinociceptive antihypertensive and cognitive benefits in rat disease models of pain, hypertension, and Alzheimer's disease. ==See also== * Agomelatine * Ramelteon * Tasimelteon 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Piromelatine」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.