翻訳と辞書 Words near each other ・ Plesitomoxia congoana ・ Plesitomoxia sericea ・ Plesitomoxia sudanensis ・ Plesk ・ Pleske's ground jay ・ Plesko ・ Pleskodāle ・ Plepat ・ Pleqërishte ・ PLER KC ・ Plerandra ・ Plerandra elegantissima ・ Plered ・ Plerergate ・ Plerguer ・ Plerixafor ・ Plerneuf ・ Plerocercoid ・ Plerodia ・ Plerogyra sinuosa ・ Pleroma ・ Pleromella ・ Pleromelloida ・ Pleromelloida conserta ・ Ples ・ Ples Gilmore ・ Ples sa zvezdama ・ Ples sa Zvezdama (Season 1) ・ Ples sa zvijezdama ・ Ples, Bistrica ob Sotli Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Plerixafor ： ウィキペディア英語版 Plerixafor Plerixafor (rINN and USAN, trade name Mozobil) is an immunostimulant used to mobilize hematopoietic stem cells in cancer patients. The stem cells are subsequently transplanted back to the patient. The drug was developed by AnorMED which was subsequently bought by Genzyme. ==History== The molecule 1,1′-()bis (), consisting of two cyclam rings linked at the amine nitrogen atoms by a 1,4-xylyl spacer, was first synthesised by Fabbrizzi et al. in 1987 to carry out basic studies on the redox chemistry of dimetallic coordination compounds. Then, it was serendipitously discovered by De Clercq that such a molecule, could have a potential use in the treatment of HIV because of its role in the blocking of CXCR4, a chemokine receptor which acts as a co-receptor for certain strains of HIV (along with the virus's main cellular receptor, CD4).Development of this indication was terminated because of lacking oral availability and cardiac disturbances. Further studies led to the new indication for cancer patients. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Plerixafor」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.