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Podoconiosis
Podoconiosis also known as nonfilarial elephantiasis〔(【引用サイトリンク】url=http://www.who.int/neglected_diseases/diseases/podoconiosis/en/ )〕 is a disease of the lymph vessels of the lower extremities that is caused by chronic exposure to irritant soils. It is the second most common cause of tropical lymphedema after filariasis, and is characterized by prominent swelling of the lower extremities, which leads to disfigurement and disability.
== Signs and symptoms ==
The primary symptom of podoconiosis is swelling and disfigurement of the lower extremities.〔Korevaar, D. A., and B. J. Visser. "Podoconiosis, a neglected tropical disease." Neth J Med. 2012 Jun;70(5):210-4. http://www.njmonline.nl/getpdf.php?id=10000840〕 The swelling can either be soft and fluid or hard and fibrotic. Multiple firm nodules may develop over time, as well as hyperkeratotic papillomata that resemble moss, which has led to the disease's alternate name of Mossy Foot. The edema of podoconiosis is usually bilateral and asymmetric. Prior to development of lymphatic failure and frank lymphedema, a prodrome consisting of itching, burning, hyperkeratosis, plantar edema, and rigid digits may occur. As with other forms of tropical lymphedema, chronic disease can lead to fusion of the toes, ulceration, and bacterial superinfection. The disease has an acute component, and sufferers may experience recurrent episodes of lower extremity warmth, firmness, and pain.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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