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Polmacoxib
Polmacoxib (Acelex) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat osteoarthritis. It was developed as CG100649 and approved for use in South Korea in February 2015.〔(【引用サイトリンク】url=http://www.prnewswire.com/news-releases/crystalgenomics-receives-mfds-approval-for-acelex-polmacoxib-300031999.html )〕 It inhibits the enzymes carbonic anhydrase and COX-2. A study in healthy volunteers showed drug effects on urinary prostaglandin metabolites for both CG100649 and celecoxib that suggest a similar cardiovascular risk profile. Further work by this group developed dose-exposure relationsships of CG100649 to guide clinical development strategies. ==See also==
* Tilmacoxib * Cimicoxib * NS-398 * Celecoxib
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Polmacoxib」の詳細全文を読む
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