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Polyvinylpolypyrrolidone (polyvinyl polypyrrolidone, PVPP, crospovidone, crospolividone or E1202) is a highly cross-linked modification of polyvinylpyrrolidone (PVP). The cross-linked form of PVP is used as a disintegrant (see also excipients) in pharmaceutical tablets.〔(Kollidon ) Accessed November 26, 2007〕〔(Polyplasdone ) Accessed January 25, 2007〕 PVPP is a highly cross-linked version of PVP, making it insoluble in water, though it still absorbs water and swells very rapidly generating a swelling force. This property makes it useful as a disintegrant in tablets. PVPP can be used as a drug, taken as a tablet or suspension to absorb compounds (so-called endotoxins) that cause diarrhoea. (''Cf.'' bone char, charcoal.) It is also used as a fining to extract impurities (via agglomeration followed by filtration). It is used in winemaking. Using the same principle it is used to remove polyphenols in beer production and thus clear beers with stable foam are produced.〔(Microsoft Word - G0294.doc )〕 One such commercial product is called ''Polyclar''. PVPP forms bonds similar to peptidic bonds in protein (especially, like proline residues) and that is why it can precipitate tannins the same way as proteins do.〔(A Novel Stabilization of Beer with Polyclar Brewbrite. Mustafa Rehmanji, Chandra Gopal, and Andrew Mola, MBAA TQ vol. 39, no. 1, 2002, pp. 24–28 )〕 PVPP has E number code E1202 and is used as a stabiliser ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Polyvinylpolypyrrolidone」の詳細全文を読む スポンサード リンク
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