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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Pregabalin ： ウィキペディア英語版 Pregabalin Pregabalin, also known as β-isobutyl-γ-Aminobutyric acid (β-isobutyl-GABA) and sold under the trade name Lyrica among others, is a medication used to in the treatment of epilepsy, neuropathic pain, fibromyalgia and generalized anxiety disorder.〔 Its use for epilepsy is as an add-on therapy for partial seizures with or without secondary generalization in adults. Common side effects include: sleepiness, confusion, trouble with memory, poor coordination, dry mouth, problem with vision, and weight gain.〔 Potentially serious side effects include angioedema, drug misuse, and an increased suicide risk.〔(【引用サイトリンク】url=http://www.drugs.com/monograph/pregabalin.html )〕 Pregabalin is a depressant that has potential for abuse. On July 28, 2005, the Drug Enforcement Administration (DEA) placed pregabalin, including its salts, and all products containing pregabalin into Schedule V of the Controlled Substances Act (CSA).〔http://www.ncbi.nlm.nih.gov/pubmed/16050051〕〔(【引用サイトリンク】title=Title 21 CFR - PART 1308 - Section 1308.15 Schedule V )〕〔http://www.deadiversion.usdoj.gov/fed_regs/rules/2005/fr0728.htm〕 Pregabalin is a structural analogue of the neurotransmitter GABA, consequently it belongs to the γ-Aminobutyric acid analogue class of antiepileptic drugs. Its a ion channel modulator that has analgesic, anticonvulsant, sedative, and anxiolytic properties. Pregabalin is a potent gabapentinoid and close analogue of GABOB (β-hydroxy-GABA), baclofen (β-(4-chlorophenyl)-GABA), and phenibut (β-phenyl-GABA).〔Jensen B, Regier LD, editors. RxFiles : Drug comparison charts. 7th ed. Saskatoon, SK: RxFiles, 2010; p.78〕 It was invented by chemist Richard Bruce Silverman of Northwestern University. Pfizer developed pregabalin as a successor to gabapentin. As of 2015 no generic version is available in the United States.〔 In the United States its costs about 3 to 6 USD per day.〔 == Medical uses == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Pregabalin」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.