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PrimPol
PrimPol is a protein encoded by the ''PRIMPOL'' gene in humans.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/gene/201973 )〕 PrimPol is a eukaryotic protein with both DNA polymerase and DNA Primase activities involved in translesion DNA synthesis. It is the first eukaryotic protein to be identified with priming activity using deoxyribonucleotides.〔〔 It is also the first protein identified in the mitochondria to have translesion DNA synthesis activities.
==Etymology==
PrimPol was identified in a bioinformatic study and initially presumed to only have primase activity. Subsequent ''in vitro'' and ''in vivo'' studies have shown it to have both primase and polymerase activities that both localise to the catalytic domain of PrimPol.〔〔 For that reason, this protein was assigned the name PrimPol.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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