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Proenkephalin : ウィキペディア英語版 | Proenkephalin
Proenkephalin (PENK), formerly known as proenkephalin A (since proenkephalin B was renamed prodynorphin), is an endogenous opioid polypeptide hormone which, via proteolyic cleavage, produces the enkephalin peptides ()enkephalin, and to a lesser extent, ()enkephalin. Upon cleavage, each proenkephalin peptide results in the generation of four copies of ()enkephalin, two extended copies of ()enkephalin, and one copy of ()enkephalin.〔 Contrarily, ()enkephalin] is predominantly synthesized from prodynorphin, which produces three copies of it per cleavage, and no copies of ()enkephalin. Other endogenous opioid peptides produced by proenkephalin include adrenorphin, amidorphin, BAM-18, BAM-20P, BAM-22P,〔 peptide B, peptide E, and peptide F. == See also ==
* Prodynorphin (Proenkephalin B) * Proopiomelanocortin (POMC)
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