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・ Proofs from THE BOOK
・ Proofs involving covariant derivatives
・ Proofs involving ordinary least squares
・ Proofs involving the addition of natural numbers
・ Proofs involving the Laplace–Beltrami operator
・ Proofs involving the Moore–Penrose pseudoinverse
・ Proofs of convergence of random variables
・ Proofs of elementary ring properties
・ Proofs of Fermat's little theorem
・ Proofs of Fermat's theorem on sums of two squares
・ Proofs of quadratic reciprocity
・ Proofs of trigonometric identities
・ Proofs related to chi-squared distribution
・ Prooftext
・ Proomphe
Proopiomelanocortin
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・ Proornis
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・ PROP
・ Prop
・ ProP (transporter)
・ Prop and Wings
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・ Prop Me Up Beside the Jukebox (If I Die)
・ Prop replica
・ Prop-
・ Prop-word
・ PROP1


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Proopiomelanocortin : ウィキペディア英語版
Proopiomelanocortin

Pro-opiomelanocortin (POMC) is a precursor polypeptide with 241 amino acid residues. POMC is synthesized from the 285-amino-acid-long polypeptide precursor pre-pro-opiomelanocortin (pre-POMC), by the removal of a 44-amino-acid-long signal peptide sequence during translation.
== Function ==

POMC is cleaved to give rise to multiple peptide hormones. Each of these peptides is packaged in large dense-core vesicles that are released from the cells by exocytosis in response to appropriate stimulation:
* α-MSH produced by neurons in the arcuate nucleus has important roles in the regulation of appetite and sexual behavior, while α-MSH secreted from the intermediate lobe of the pituitary regulates the production of melanin.
* ACTH is a peptide hormone that regulates the secretion of glucocorticoids from the adrenal cortex.
* β-Endorphin and ()enkephalin are endogenous opioid peptides with widespread actions in the brain.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Proopiomelanocortin」の詳細全文を読む



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