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Proteotoxicity : ウィキペディア英語版 | Proteotoxicity Proteotoxicity is toxicity caused by proteins, usually of misfolded proteins. Examples of proteotoxic proteins are the prion protein, and several proteins that when mutated result in neurodegenerative disease and produce aggregates in brain tissues, such as amyloid-beta in Alzheimer's disease and huntingtin in Huntington's disease. It is hypothesized that chaperones, proteins that assist protein folding antagonize proteotoxicity. ==See also==
*Proteostasis
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Proteotoxicity」の詳細全文を読む
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