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Pseudoporphyria : ウィキペディア英語版
Pseudoporphyria

Pseudoporphyria (also known as "Pseudoporphyria cutanea tarda") is a bullous photosensitivity that clinically and histologically mimics porphyria cutanea tarda. The difference is that no abnormalities in urine or serum porphyrin is noted on laboratories. Pseudoporphyria has been reported in patients with chronic renal failure treated with hemodialysis and in those with excessive exposure to ultraviolet A (UV-A) by tanning beds.〔http://www.emedicine.com/derm/TOPIC358.HTM〕
==Pathophysiology==
The precise pathophysiologic mechanism of pseudoporphyria is not fully understood. Some drugs, especially non steroidal anti-inflammatory drugs, can trigger pseudoporphyria in the presence of ultraviolet light.
The pathophysiology of pseudoporphyria associated with hemodialysis has not been fully explained. Aluminum hydroxide has been implicated in hemodialysis-associated pseudoporphyria. Aluminum hydroxide is found in dialysis solution and has been shown to produce a porphyrialike disorder after long-term administration in rats.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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