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Ptc1 is a type Two C phosphatase involved in the mating decision of yeast. Ptc1 competes with Fus3 for control of the 4 phosphorylation sites on the scaffold protein Ste5. Presence of the mating pheromone α-factor causes Ptc1 to be recruited to Ste5. This recruitment takes place via a 4 amino acid motif in the Ste5 phosphosites. Ptc1 is also involved in regulating the osmotic stress of yeast, especially via inactivation of Hog1, a member of the MAPK pathway. This inactivation occurred as a result of dephosphorylation of the phosphotheronine but not the phosphotyrosine residue in the phosphorylation lip of Hog1. It can be localized to the cytoplasm and nucleus.〔 == Biological Processes == Ptc1 is involved in the following biological processes:〔 *Inactivation of MAPK activity in osmosensory signalling pathways *Mitochondrial inheritance *Pheromone-dependent signal transduction in conjugation with cellular fusion *Protein dephosphorylation *tRNA splicing via. Endonucleolytic cleavage and ligation 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Ptc1」の詳細全文を読む スポンサード リンク
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