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Purpurogallin : ウィキペディア英語版 | Purpurogallin
Purpurogallin is a red, crystalline compound, and the aglycon of several glycosides from nutgalls and oak barks.〔Molecular structure and antioxidant specificity of purpurogallin in three types of human cardiovascular cells. Tai-Wing Wu, Ling-Hua Zeng, Jun Wu, Kwok-Pui Fung, Richard D. Weisel, Andrew Hempel and Norman Camerman, Biochemical Pharmacology, Volume 52, Issue 7, 11 October 1996, Pages 1073-1080, 〕 It can inhibit hydroxyestradiol methylation by catechol-O-methyltransferase.〔Benzotropolone inhibitors of estradiol methylation: kinetics and in silico modeling studies. Joshua D. Lambert, Dapeng Chena, Ching Y. Wang, Ni Ai, Shengmin Sang, Chi-Tang Ho, William J. Welsh and Chung S. Yang, Bioorganic & Medicinal Chemistry, Volume 13, Issue 7, 1 April 2005, Pages 2501-2507, 〕 It potently and specifically inhibits TLR1/TLR2 activation pathway.〔Discovery of Small-Molecule Inhibitors of the TLR1/TLR2 Complex. K. Cheng, X. Wang, S. Zhang, H. Yin, Angew. Chem. Int. Ed. Early View, 〕 ==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Purpurogallin」の詳細全文を読む
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