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Quadazocine : ウィキペディア英語版
Quadazocine

Quadazocine (WIN-44,441) is an opioid antagonist of the benzomorphan family which is used in scientific research. It acts as a silent antagonist at all three of the major opioid receptors—μ, κ, and δ,〔 but with a significant preference in affinity for the μ receptor and the κ2 subtype. As such, it has been touted as a "κ2-selective" antagonist, though, of course, this is not entirely accurate on account of its similar affinity for the μ receptor.〔〔 As would be expected, quadazocine reverses the effects (e.g., analgesia) of opioid agonists like morphine and fentanyl in animals.〔
==References==



抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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