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・ R-2 Mala-class swimmer delivery vehicle
・ R-2000 program
・ R-21 (missile)
・ R-23 (missile)
・ R-25 Vulkan
・ R-26 (missile)
・ R-26 (salon)
・ R-27 (air-to-air missile)
・ R-27 Zyb
・ R-29 Vysota
・ R-29RM Shtil
・ R-29RMU Sineva
・ R-29RMU2 Layner
・ R-3 (tank)
・ R-3 motorway (Spain)
R-30490
・ R-31 (missile)
・ R-33 (missile)
・ R-36 (missile)
・ R-360
・ R-37 (missile)
・ R-39 Rif
・ R-390A
・ R-39M
・ R-4 (missile)
・ R-4 motorway (Spain)
・ R-40 (missile)
・ R-4066
・ R-406A
・ R-407A


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R-30490 : ウィキペディア英語版
R-30490

R-30490 is an opioid analgesic related to the highly potent animal tranquilizer carfentanil, and with only slightly lower potency. It was first synthesised by a team of chemists at Janssen Pharmaceutica led by Paul Janssen, who were investigating the structure-activity relationships of the fentanyl family of drugs. R-30490 was found to be the most selective agonist for the mu opioid receptor out of all the fentanyl analogues tested, but it has never been introduced for medical use in humans, although the closely related drug sufentanil is widely used for analgesia and anesthesia during major surgery.
Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.
==References==



抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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