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RAET1L Retinoic acid early transcript 1L (RAET1L) is a cell surface glycoprotein encoded by ''RAET1L'' gene located on the chromosome 6. RAET1L is related to MHC class I molecules, but its gene maps outside the MHC locus.〔 RAET1L is composed of the α1α2 domain and is linked to the cell membrane by the GPI anchor.〔 It functions as a stress-induced ligand for NKG2D receptor.〔 Its expression is, for example, triggered in course of HCMV infection, but HCMV alters its function.〔 HCMV-encoded UL16 glycoprotein retains ULBP6 inside the cells, preventing it from reaching the cell surface and being exposed to cells of the immune system.〔 ==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「RAET1L」の詳細全文を読む
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