翻訳と辞書 Words near each other ・ RAL ・ RAL colour standard ・ Ral Donner ・ Ral Grad ・ Ral Partha Enterprises ・ Ral Partha Vogelbacher ・ RALA ・ RaLa Experiment ・ Ralaghan ・ Ralaghan Man ・ Ralahine ・ Ralahyne ・ Ralam Glacier ・ Ralambo ・ Ralang Monastery ・ RALB ・ Ralbitz-Rosenthal ・ RALBP1 ・ Ralco Hydroelectric Plant ・ Ralco National Reserve ・ Ralcorp ・ Rale ・ Rale Micic ・ Rale Rasic ・ Raleb Majadele ・ Ralegan Siddhi ・ Ralegan Therpal ・ Ralegaon ・ Ralegaon (Vidhan Sabha constituency) ・ Ralegh Radford Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク RALB ： ウィキペディア英語版 RALB Ras-related protein Ral-B (RalB) is a protein that in humans is encoded by the ''RALB'' gene on chromosome 2. This protein is one of two isoforms of the Ral protein, the other being RalA, and part of the Ras GTPase family. RalA functions as a molecular switch to activate a number of biological processes, majorly cell division and transport, via signaling pathways.〔 Its biological role thus implicates it in many cancers.〔 == Structure == The Ral isoforms share an 80% overall match in amino acid sequence and 100% match in their effector-binding region. The two isoforms mainly differ in the C-terminal hypervariable region, which contains multiple sites for post-translational modification, leading to diverging subcellular localization and biological function. For example, phosphorylation of Serine 194 on RalA by the kinase Aurora A results in the relocation of RalA to the inner mitochondrial membrane, where RalA helps carry out mitochondrial fission; whereas phosphorylation of Serine 198 on RalB by the kinase PKC results in the relocation of RalB to other internal membranes and activation of its tumorigenic function.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「RALB」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.