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・ Ranganathan Street
・ Ranganathapuram
・ Ranganathaswamy Temple
・ Ranganathaswamy Temple, Bangalore
・ Ranganathaswamy Temple, Nellore
・ Ranganathaswamy Temple, Nirthadi
・ Ranganathaswamy Temple, Shivanasamudra
・ Ranganathaswamy Temple, Srirangam
・ Ranganathaswamy Temple, Srirangapatna
・ Ranganathaswamy Temple, Vavilavalasa
・ Ranganathittu Bird Sanctuary
・ Ranganayaki
・ Ranganayaki (film)
・ Ranganayaki Rajagopalan
・ RanGAP
RANGAP1
・ Rangapara
・ Rangappa Hogbitna
・ Rangapur
・ Rangapur, Belgaum
・ Rangapur, Lumbini
・ Rangapur, Manchal mandal
・ Rangapur, Nalgonda
・ Rangapur, Narayani
・ Rangapur, Shabad mandal
・ Rangapura Vihara
・ Rangapuram Khandrika
・ Rangar Nangal
・ Rangarajan
・ Rangarajan Kumaramangalam


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RANGAP1 : ウィキペディア英語版
RANGAP1


Ran GTPase-activating protein 1 is an enzyme that in humans is encoded by the ''RANGAP1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5905 )
== Function ==

RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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