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Ras and EF-hand domain-containing protein also known as Ras-related protein Rab-45 is a protein that in humans is encoded by the RASEF gene. The RASEF gene is located on chromosome 9 (9q21.32). == Introduction == RASEF belongs to the small GTPase family, which means that it’s able to hydrolyse a molecule of GTP; known for its unusual conformation. In the small GTPase family it is classified in the RAS domain, a special group of oncogenes and oncoproteins that take part in the synthesis of molecules related to cell reproduction.〔 A feature of RASEF is its N-terminal EF-hand domain with C-terminal Rab-homology domain, that enables it to bind calcium.〔 Lately, RASEF has been studied for its role as an oncoprotein. Investigating which mutations affect it and how we could inhibit them could allow us to fight cancers that have an elevated mortality rate, such as lung cancer.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「RASEF」の詳細全文を読む スポンサード リンク
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