翻訳と辞書 Words near each other ・ Raseśvara ・ Rasfa ・ Rasfand ・ Rasfijan ・ Rasgan ・ Rasganço ・ RasGas ・ RasGEF domain ・ RASGEF1A ・ Rasgetheemu (Raa Atoll) ・ RASGRF1 ・ RASGRF2 ・ RASGRP1 ・ RASGRP2 ・ RASGRP3 ・ RASGRP4 ・ Rasgueado ・ Rasgulla ・ Rash ・ Rash (disambiguation) ・ Rash (film) ・ Rash (novel) ・ Rash (surname) ・ Rash Behari Bose ・ Rash Behari Datta ・ Rash Behari Ghosh ・ Rash Decisions ・ Rash guard ・ Rash promise ・ Rash, Alabama Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク RASGRP4 ： ウィキペディア英語版 RASGRP4 RAS guanyl releasing protein 4 is a protein in humans that is encoded by the RASGRP4 gene in chromosome 19. 〔 (【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=retrieve&list_uids=115727 )〕 The protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors. It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands. This protein was shown to activate H-Ras in a cation-dependent manner in vitro. Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways. Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development. Multiple transcript variants encoding different isoforms have been found for this gene. (by RefSeq, Apr 2009 ). == References == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「RASGRP4」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.