翻訳と辞書 Words near each other ・ RBM22 ・ RBM23 ・ RBM25 ・ RBM26 ・ RBM28 ・ RBM3 ・ RBM33 ・ RBM34 ・ RBM39 ・ RBM4 ・ RBM47 ・ RBM5 ・ RBM6 ・ RBM7 ・ RBM8A ・ RBM9 ・ RBMG Records ・ RBMK ・ RBMS ・ RBMS1 ・ RBMX ・ RBN ・ RBN-4 gas field ・ RBNS Sabha (FFG-90) ・ RBO ・ RBP ・ RBP1 ・ RBP2 ・ RBP3 ・ RBPJ Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク RBM9 ： ウィキペディア英語版 RBM9 RNA binding motif protein 9, also known as RBM9 or FOX-2, is a protein which in humans is encoded by the ''RBM9'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23543 )〕 == Function == RBM9 is one of several human genes similar to the ''C. elegans'' gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.〔 RBM9, as determined by CLIP-seq, binds near alternatively spliced exons and regulates the inclusion or exclusion of exons during alternative splicing by binding in introns either downstream (inclusion) or upstream (exon skipping) of exons. Its presence is important for stem cell survival and knockdowns of RBM9 activate markers for apoptosis. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「RBM9」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.