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RDE-1
RDE-1 (''R''NAi-''DE''fective ''1'') is a primary Argonaute protein required for RNA-mediated interference (RNAi) in ''Caenorhabditis elegans''. The rde-1 gene locus was first characterized in ''C. elegans'' mutants resistant to RNAi, and is a member of a highly conserved Piwi gene family that includes plant, Drosophila, and vertebrate homologs. == Role in RNAi pathway ==
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