翻訳と辞書 Words near each other ・ Rhabdophis chrysargos ・ Rhabdophis himalayanus ・ Rhabdophis nigrocinctus ・ Rhabdophis subminiatus ・ Rhabdophis tigrinus ・ Rhabdophloeus ・ Rhabdophyllia ・ Rhabdopleura normani ・ Rhabdopleurida ・ RGIT ・ RGK ・ RGK Center for Philanthropy and Community Service ・ RGL2 ・ RGM-40 ・ RGM-59 Taurus ・ RGMA ・ RGMB ・ Rgn ・ RGN hand grenade ・ RGO (disambiguation) ・ RGO hand grenade ・ Rgotina ・ Rgošte ・ RGP ・ RGP3 ・ RGPD5 ・ RGR ・ RGS ・ RGS Springfield ・ RGS The Grange Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク RGMA ： ウィキペディア英語版 RGMA Repulsive guidance molecule A also known as RGMa is a protein that in humans is encoded by the ''RGMA'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56963 )〕 == Function == RGMa is a repulsive guidance molecule for retinal axons. Furthermore neogenin functions as a receptor for RGM. Neogenin overexpression and RGM downexpression in the developing embryonic neural tube induces apoptosis. The apoptotic activity of neogenin in the neural tube is associated with cleavage of its cytoplasmic domain by caspases. RGMA belongs to a family of repulsive guidance molecules that are (glycosylphosphatidylinositol)-linked cell-membrane-associated proteins. The three proteins, RGMa (this protein), RGMb and RGMc are 40-50% identical to each other, and share similarities in predicted protein domains and overall structure. All three RGM proteins appear capable of binding selected BMPs (bone morphogenetic proteins). RGMs may play inhibitory roles in prostate cancer by suppressing cell growth, adhesion, migration and invasion. RGMs can coordinate Smad-dependent and Smad-independent signalling of BMPs in prostate cancer and breast cancer cells. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「RGMA」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.