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RHOBTB3
Rho-related BTB domain-containing protein 3 is a protein that in humans is encoded by the ''RHOBTB3'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22836 )〕
==Model organisms==
Model organisms have been used in the study of RHOBTB3 function. A conditional knockout mouse line, called ''Rhobtb3tm1a(KOMP)Wtsi'' was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.〔 Twenty three tests were carried out on mutant mice and four significant abnormalities were observed.〔 Homozygote mutant males had a decreased body weight and abnormal tooth morphology; females had decreased forepaw grip strength and both sexes had a decreased body length.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「RHOBTB3」の詳細全文を読む
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