翻訳と辞書 Words near each other ・ Rhostrehwfa ・ Rhostryfan railway station ・ Rhostyllen ・ Rhostyllen railway station ・ Rhosus ・ Rhosus (moth) ・ Rhosybol ・ Rhosydd ・ Rhosydd Castell-du & Plas-y-bettws ・ Rhosydd Llanwrthwl ・ Rhosydd Quarry ・ Rhosygadair Newydd ・ Rhosymedre ・ Rhosymedre (hymn tune) ・ Rhosymedre Halt railway station ・ RHOT1 ・ RHOT2 ・ Rhotacism ・ Rhotacization ・ Rhotia ・ Rhotic ・ Rhotic consonant ・ Rhoticism ・ Rhoticity in English ・ Rhoud El Baguel ・ Rhourde El Baguel oil field ・ Rhourde Nouss gas field ・ Rhovanion ・ RHOXF1 ・ RHOXF2 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク RHOT1 ： ウィキペディア英語版 RHOT1 Mitochondrial Rho GTPase 1 (MIRO1) is an enzyme that in humans is encoded by the ''RHOT1'' gene on chromosome 17.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55288 )〕 As a Miro protein isoform, the protein facilitates mitochondrial transport by attaching the mitochondria to the motor/adaptor complex. Through its key role in mitochondrial transport, RHOT1 is involved in mitochondrial homeostasis and apoptosis, as well as Parkinson’s disease (PD) and cancer.〔 ==Structure== In mammals, RHOT1 is one of two Miro isoforms. Both isoforms share a structure consisting of two EF-hand motifs linking two GTP-binding domains and a C-terminal transmembrane domain that attaches the protein to the outer mitochondrial membrane (OMM).〔 The EF-hand motifs serve as binding sites for the adaptor protein Milton and the kinesin heavy chain. These domains can also bind calcium ions, and the binding results in a conformational change that dissociates the mitochondrial surface from kinesin.〔〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「RHOT1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.