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RIC3
RIC-3 also known as resistance to inhibitors of cholinesterase 3 is a chaperone protein that in humans is encoded by the ''RIC3'' gene. The RIC3 gene was first discovered in ''C. elegans''. RIC-3 protein is conserved in most animals and influences the maturation of various ligand gated ion channels including the serotonin 5-HT3 receptor and nicotinic acetylcholine receptors,〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79608 )〕 particularly the homomeric α7 nicotinic receptor. RIC-3 enhances currents generated by these receptors by expediting receptor transport to the cell surface and by increasing receptor number. == References ==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「RIC3」の詳細全文を読む
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