翻訳と辞書 Words near each other ・ Rigby's Buildings ・ Rigby's La Plaza Historic District ・ Rig Sefid, Dehpir-e Shomali ・ Rig Sefid, Robat ・ Rig Sefid, Zagheh ・ Rig standpipe ・ Rig Zardan ・ Rig, Jask ・ Rig, Lirdaf ・ Rig, West Virginia ・ Rig-e Bala ・ Rig-e Jenn ・ Rig-e Kaput ・ Rig-e Muri ・ Rig-e Sefid, Selseleh ・ RIG-I ・ RIG-I-like receptor ・ Riga ・ Riga (disambiguation) ・ Riga (moped) ・ Riga (surname) ・ Riga (Vidhan Sabha constituency) ・ Riga Academy ・ Riga Autobus Factory ・ Riga Aviation Museum ・ Riga Black Balsam ・ Riga Bridge (Velikaya River) ・ Riga Business School ・ Riga Castle ・ Riga Cathedral Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク RIG-I ： ウィキペディア英語版 RIG-I RIG-I (retinoic acid-inducible gene 1) is a RIG-I-like receptor dsRNA helicase enzyme that is encoded (in humans) by the ''DDX58'' gene. RIG-I is part of the RIG-I-like receptor family, which also includes MDA5 and LGP2, and functions as a pattern recognition receptor that is a sensor for viruses such as influenza A, Sendai virus, and flavivirus. Certain retroviruses, such as HIV-1, encode a protease that directs RIG-1 to the lysosome for degradation, and thereby evade RIG-1 mediated signaling. RIG-I typically recognizes short (< 4000nt) 5′ triphosphate uncapped double stranded or single stranded RNA. RIG-I and MDA5 are involved in activating MAVS and triggering an antiviral response. RIG-I is also able to detect non-self 5′-triphosphorylated dsRNA transcribed from AT-rich dsDNA by DNA-dependent RNA polymerase III (Pol III). For many viruses, effective RIG-I-mediated antiviral responses are dependent on functionally active LGP2. == Function == DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. RIG-I contains a RNA helicase-DEAD box motifs and a caspase recruitment domain (CARD). RIG-I is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23586 )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「RIG-I」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.