翻訳と辞書 Words near each other ・ Ripon High School ・ Ripon High School (California) ・ Ripon High School, Wisconsin ・ Ripon Jewel ・ Ripon Lodge ・ Ripon Racecourse ・ Ripon railway station ・ Ripon Red Hawks ・ Ripiceni ・ Ripieno ・ Ripieno concerto ・ Ripiphoridae ・ Ripiro Beach ・ RipIt ・ Ripit ・ RIPK1 ・ RIPK2 ・ RIPK3 ・ RIPK4 ・ RIPK5 ・ Ripkin ・ Ripky ・ Ripky Raion ・ RIPL ・ Ripley ・ Ripley (CDP), New York ・ Ripley (crater) ・ Ripley (name) ・ Ripley Academy ・ Ripley and New Albany Railroad Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク RIPK1 ： ウィキペディア英語版 RIPK1 Receptor-interacting serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the ''RIPK1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8737 )〕 RIPK1 is known to have function in a variety of cellular pathways including the NF-κB pathway and programmed necrotic cell death (necroptosis). == Function == Although, RIPK1 has been primarily studied in the context of TNFR signaling, RIPk1 is also activated in response to diverse stimuli. The kinase domain, while important for necroptotic (programmed necrotic) functions, it appears dispensable for pro-survival roles. Kinase activity of RIPK1 is also required for RIPK1-dependent apoptosis in conditions of IAP1/2 depletion, TAK1inhibition/depletion, RIPK3 depletion or MLKL depletion. Also, proteolytic processing of RIPk1, through both caspase-dependent and -independent mechanisms, triggers lethality that is dependent on the generation of one or more specific C-terminal cleavage product(s) of RIPk1 upon stress. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「RIPK1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.