翻訳と辞書 Words near each other ・ RNAs present in environmental samples ・ RNAS Pulham ・ RNAS St Merryn (HMS Vulture) ・ RNAS Stretton (HMS Blackcap) ・ RNAS Tresco ・ RNAS Yeovilton (HMS Heron) ・ RNase D ・ RNase E 5' UTR element ・ RNase MRP ・ RNase PH ・ RNase PhyM ・ RNase R ・ RNASE1 ・ RNASEH1 ・ RNASEH2A ・ RNASEH2B ・ RNASET2 ・ RNB ・ RNB Global University ・ RNB Research ・ RNC ・ RNC 8 ・ RNC Media ・ RNC Welcoming Committee ・ RncO ・ RNCP ・ RND ・ Rnd ・ Rnd (GTPase) ・ Rnd1 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク RNASEH2B ： ウィキペディア英語版 RNASEH2B Ribonuclease H2, subunit B is a protein that in humans is encoded by the ''RNASEH2B'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/gene/79621 )〕 RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C), and degrades the RNA of RNA:DNA hybrids. The non-catalytic B subunit of RNase H2 is thought to play a role in DNA replication.〔 Mutations in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).〔 ==Model organisms== Model organisms have been used in the study of RNASEH2B function. A conditional knockout mouse line, called ''Rnaseh2btm1a(EUCOMM)Wtsi'' was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.〔 Twenty four tests were carried out on mutant mice and three significant abnormalities were observed.〔 No homozygous mutant embryos were identified during gestation, and therefore none survived until weaning. The remaining tests were carried out on heterozygous mutant adult mice and an increased susceptibility to bacterial infection was observed in female animals.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「RNASEH2B」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.