翻訳と辞書 Words near each other ・ Ro-langs ・ Ro-Marong Nigeria ・ Ro-Tel ・ Ro.Go.Pa.G. ・ Ro01-6128 ・ Ro10-5824 ・ Ro15-4513 ・ RO2 ・ Ro4-1539 ・ RO4491533 ・ Ro48-6791 ・ Ro48-8684 ・ Ro4938581 ・ Ro5-2904 ・ Ro5-4864 ・ RO5166017 ・ Ro60-0175 ・ Ro60-0213 ・ Ro64-6198 ・ Ro67-4853 ・ ROA ・ Roa ・ ROA (artist) ・ Roa (genus) ・ Roa de Duero ・ Roa Island ・ Roa Malaka ・ Roa Ridge ・ Roa Station ・ ROA Time Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク RO5166017 ： ウィキペディア英語版 RO5166017 RO-5166017 is a drug developed by Hoffmann-La Roche which acts as a potent and selective agonist for the trace amine-associated receptor 1, with no significant activity at other targets. This is important for the study of the TAAR1 receptor, as while numerous other compounds are known which act as TAAR1 agonists, such as methamphetamine, MDMA and 3-iodothyronamine, all previously known TAAR1 agonists are either weak and rapidly metabolized (endogenous ligands), or have strong pharmacological activity at other targets (amphetamines, thyronamines), making it very difficult to assess which effects are due to TAAR1 activation. The discovery of RO-5166017 allows purely TAAR1 mediated effects to be studied, and in animal studies it was shown to prevent stress-induced hyperthermia and block dopamine-dependent hyperlocomotion, as well as blocking the hyperactivity which would normally be induced by an NMDA antagonist. ==See also== * EPPTB * O-Phenyl-3-iodotyramine 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「RO5166017」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.