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RSPO1
R-spondin-1 is a secreted protein that in humans is encoded by the ''Rspo1'' gene, found on chromosome 1.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=284654 )〕 In humans, it interacts with WNT4 in the process of female sex development. Loss of function can cause female to male sex reversal. Furthermore, it promotes canonical WNT/β catenin signaling. ==Structure== The protein has two cysteine-rich, furin-like domains and one thrombospondin type 1 domain.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「RSPO1」の詳細全文を読む
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