翻訳と辞書 Words near each other ・ Ras Shorty I ・ Ras Siyyan ・ Ras subfamily ・ Ras superfamily ・ RAS syndrome ・ Ras Tabouda ・ Ras Tanajib Airport ・ Ras Tanura ・ Ras Tanura Airport ・ Ras Tarkhan ・ Ras Thavas ・ RAS-1 ・ RAS-associated autoimmune leukoproliferative disorder ・ Ras-e Jonubi ・ Ras-e Sharqi ・ Ras-GRF1 ・ Ras-I Dowling ・ Ras2 ・ Rasa ・ Rasa (aesthetics) ・ Rasa (band) ・ Rasa (theology) ・ Rasa Dentremont ・ Rasa Drazdauskaitė ・ Rasa Imanalijeva ・ Rasa Island ・ Rasa Juknevičienė ・ Rasa Kaušiūtė ・ Rasa Komuter station ・ Rasa Leleivytė Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Ras-GRF1 ： ウィキペディア英語版 Ras-GRF1 Ras-GRF1 is a guanine nucleotide exchange factor. Its function is to release guanosine diphosphate, GDP, from the signaling protein RAS, thus increasing the activity of RAS by allowing it to bind to guanosine triphosphate, GTP, returning it to its active state. In this way, Ras-GRF1 has a key role in regulating the RAS signaling pathway. Ras-GRF1 knockout mice have been shown to have learning and memory deficits associated with dysregulation of this pathway. Ras-GRF1 has also been shown to be upstream from IGF1, allowing it to control growth in mice. Although it is sometimes known as CDC25, it should not be confused with Cdc25. Ras-GRF1 is a paternally expressed imprinted gene, meaning that only the paternal allele of the gene is translated into protein. Disruption of this epigenetic imprinting also produces learning and memory deficits in neonatal mice. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Ras-GRF1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.