翻訳と辞書 Words near each other ・ Rebel Soul Sound System ・ Rebel Space ・ Rebel Spirit ・ Rebel Sport ・ Rebecca Zadig ・ Rebecca Zanetti ・ Rebecca Zhu ・ Rebecca Zlotowski ・ Rebecca's Daughters ・ Rebecca's Empire ・ Rebecca's Revival ・ Rebecca's Tale ・ Rebecca's Wedding Day ・ Rebecca, Georgia ・ Rebecca/Eureka transponding radar ・ Rebeccamycin ・ Rebecchino ・ Rebecka ・ Rebecka Belldegrun ・ Rebecka Hemse ・ Rebecka Liljeberg ・ Rebecka Mendelssohn ・ Rebecka Törnqvist ・ Rebecq ・ Rebecques ・ Rebeka Bobanj ・ Rebeka Dremelj ・ Rebeka Kim ・ Rebeka Kárpáti ・ Rebeka Montoya Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Rebeccamycin ： ウィキペディア英語版 Rebeccamycin Rebeccamycin is a weak topoisomerase I inhibitor isolated from ''Streptomyces sp.'' It is structurally similar to staurosporine, but does not show any inhibitory activity against protein kinases. It shows significant antitumor properties in vitro (IC50=480nM against mouse B16 melanoma cells and IC50=500nM against P388 leukemia cells). == References == *''Production and biological activity of rebeccamycin, a novel antitumor agent'': J.A. Bush, et al.; J. Antibiot. (Tokyo) 40, 668 (1987) *''Syntheses and biological activities (topoisomerase inhibition and antitumor and antimicrobial properties) of rebeccamycin analogues bearing modified sugar moieties and substituted on the imide nitrogen with a methyl group'' F. Anizon, et al.; J. Med. Chem. 40, 3456 (1997) *''DNA cleavage by topoisomerase I in the presence of indolocarbazole derivatives of rebeccamycin'': C. Bailly, et al.; Biochemistry 36, 3917 (1997) *''Calories from carbohydrates: energetic contribution of the carbohydrate moiety of rebeccamycin to DNA binding and the effect of its orientation on topoisomerase I inhibition'': C. Bailly, et al.; Chem. Biol. 6, 277 (1999) 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Rebeccamycin」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.